Tag

Tumor Growth
New mechanism highlights risks of circadian disruption and supports timed cancer treatment. Source: https://www.eurekalert.org/news-releases/497871# NEWS RELEASE 30-APR-2019 Disrupting normal circadian rhythms promotes tumor growth and suppresses the effects of a tumor-fighting drug, according to a new study publishing April 30 in the open-access journal PLOS Biology by Yool Lee, Amita Sehgal, and colleagues at the University of Pennsylvania....
Read More
Aiello I, Fedele MLM, Román F, Marpegan L, Caldart C, Chiesa JJ, Golombek DA, Finkielstein CV, Paladino N. Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation. Sci Adv. 2020 Oct 14;6(42):eaaz4530. doi: 10.1126/sciadv.aaz4530. PMID: 33055171; PMCID: PMC7556830. Abstract Circadian disruption negatively affects physiology, posing a global health threat that manifests in proliferative, metabolic,...
Read More
Citation: Blask DE, Dauchy RT, Dauchy EM, Mao L, Hill SM, Greene MW, et al. (2014) Light Exposure at Night Disrupts Host/Cancer Circadian Regulatory Dynamics: Impact on the Warburg Effect, Lipid Signaling and Tumor Growth Prevention. PLoS ONE 9(8): e102776. https://doi.org/10.1371/journal.pone.0102776 Abstract The central circadian clock within the suprachiasmatic nucleus (SCN) plays an important role in...
Read More