Tag

Shift Work
01
Sep

EMFSA August 2024 Newsletter

September 1, 2024
Photo by Alex Bertha on Unsplash Link to our free August 2024 newsletter https://mailchi.mp/emfsa/august2024news
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07
Dec

Daytime eating prevents internal circadian misalignment and glucose intolerance in night work

December 7, 2021
Daytime eating prevents internal circadian misalignment and glucose intolerance in night workSarah L. ChellappaJingyi QianNina VujovicChristopher J. MorrisArlet NedeltchevaHoa NguyenNishath RahmanSu WeiHengLauren KellyKayla Kerlin-MonteiroSuhina SrivastavWei WangDaniel AeschbachCharles A. CzeislerSteven A.SheaGail K. AdlerMarta GarauletFrank A. J. L. ScheerSci. Adv., 7 (49), eabg9910. • DOI: 10.1126/sciadv.abg9910 Abstract Night work increases diabetes risk. Misalignment between the central circadian...
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03
Jul

Impact of Shift Work and Long Working Hours on Worker Cognitive Functions: Current Evidence and Future Research Needs

July 3, 2021
Leso, V.; Fontana, L.; Caturano, A.; Vetrani, I.; Fedele, M.; Iavicoli, I. Impact of Shift Work and Long Working Hours on Worker Cognitive Functions: Current Evidence and Future Research Needs. Int. J. Environ. Res. Public Health 2021, 18, 6540. https://doi.org/10.3390/ijerph18126540 Abstract Particular working conditions and/or organization of working time may cause important sleep disturbances that have been proposed...
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22
Jun

Effects of sleep deprivation on endothelial function in adult humans: a systematic review

June 22, 2021
Holmer, B.J., Lapierre, S.S., Jake-Schoffman, D.E. et al. Effects of sleep deprivation on endothelial function in adult humans: a systematic review. GeroScience 43, 137–158 (2021). https://doi.org/10.1007/s11357-020-00312-y Abstract Sleep deprivation is highly prevalent and is associated with increased cardiovascular disease (CVD) morbidity and mortality. Age-related alterations in sleep and chronobiology may exaggerate CVD susceptibility in older individuals. The mechanisms responsible for...
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13
Jun

Circadian clocks and insulin resistance

June 13, 2021
Stenvers, D.J., Scheer, F.A.J.L., Schrauwen, P. et al. Circadian clocks and insulin resistance. Nat Rev Endocrinol 15, 75–89 (2019). https://doi.org/10.1038/s41574-018-0122-1 Abstract Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a major cause of morbidity and mortality. The circadian timing system consists of a central brain clock in the hypothalamic suprachiasmatic nucleus and various peripheral...
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13
Jun

Interconnection between circadian clocks and thyroid function

June 13, 2021
Ikegami, K., Refetoff, S., Van Cauter, E. et al. Interconnection between circadian clocks and thyroid function. Nat Rev Endocrinol 15, 590–600 (2019). https://doi.org/10.1038/s41574-019-0237-z Abstract Circadian rhythmicity is an approximately 24-h cell-autonomous period driven by transcription–translation feedback loops of specific genes, which are referred to as ‘circadian clock genes’. In mammals, the central circadian pacemaker, which is located in the hypothalamic...
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16
May

Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet

May 16, 2021
Gutierrez Lopez DE, Lashinger LM, Weinstock GM, Bray MS. Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet. Cell Metab. 2021 May 4;33(5):873-887. doi: 10.1016/j.cmet.2021.03.015. Epub 2021 Mar 30. PMID: 33789092. Abstract The molecular circadian clock and symbiotic host-microbe relationships both evolved as mechanisms that enhance metabolic responses to environmental challenges....
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13
May

Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases

May 13, 2021
Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends in Pharmacological Sciences. 2018 Sep;39(9):812-827. DOI: 10.1016/j.tips.2018.07.003. Highlights Although circadian rhythm disruption (CRD) was typically considered to be a risk for chronic diseases solely for shift workers (∼20%...
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02
May

Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia

May 2, 2021
Hayter, E.A., Wehrens, S.M.T., Van Dongen, H.P.A. et al. Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia. Nat Commun 12, 2472 (2021). https://doi.org/10.1038/s41467-021-22788-8 Abstract Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set...
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01
May

How the Intensity of Night Shift Work Affects Breast Cancer Risk

May 1, 2021
Szkiela, M.; Kusideł, E.; Makowiec-Dąbrowska, T.; Kaleta, D. How the Intensity of Night Shift Work Affects Breast Cancer Risk. Int. J. Environ. Res. Public Health 2021, 18, 4570. https://doi.org/10.3390/ijerph18094570 Abstract Background—In 2019, the IARC concluded that “night shift work is probably carcinogenic to humans (Group 2A), based on limited evidence from human epidemiological studies and sufficient evidence of...
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