Tag

Retinal Ganglion Cells
09
Jul

Chapter 21 – Retina and melanopsin neurons

July 9, 2021
La Morgia C, Carelli V, Sadun AA. Retina and melanopsin neurons. Handb Clin Neurol. 2021;179:315-329. doi: 10.1016/B978-0-12-819975-6.00020-0. PMID: 34225972. Abstract Melanopsin retinal ganglion cells (mRGCs) are the third class of retinal photoreceptors with unique anatomical, electrophysiological, and biological features. There are different mRGC subtypes with differential projections to the brain. These cells contribute to many...
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24
May

Partial recovery of visual function in a blind patient after optogenetic therapy

May 24, 2021
Sahel, JA., Boulanger-Scemama, E., Pagot, C. et al. Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med (2021). https://doi.org/10.1038/s41591-021-01351-4 Abstract Optogenetics may enable mutation-independent, circuit-specific restoration of neuronal function in neurological diseases. Retinitis pigmentosa is a neurodegenerative eye disease where loss of photoreceptors can lead to complete blindness. In a blind patient, we combined...
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