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Optical
Neurochem Int. 2019 Feb 27. pii: S0197-0186(18)30627-2. doi: 10.1016/j.neuint.2019.02.018. [Epub ahead of print] Abstract Neurones are dependent on their mitochondria to produce the necessary amounts of ATP for survival. Retinal ganglion cells (RGCs) have a particularly large number of mitochondria which-unlike neurones in the brain-are exposed to visual light of 400-850 nm. Here we demonstrate that short...
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Excerpts: Karunarathne’s lab found that blue light exposure causes retinal to trigger reactions that generate poisonous chemical molecules in photoreceptor cells. “It’s toxic. If you shine blue light on retinal, the retinal kills photoreceptor cells as the signaling molecule on the membrane dissolves,” Kasun Ratnayake, a PhD student researcher working in Karunarathne’s cellular photo chemistry...
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