Tag

Neurodegenerative Diseases
03
Apr

Adult Neurogenesis under Control of the Circadian System

April 3, 2022
Ali AAH, von Gall C. Adult Neurogenesis under Control of the Circadian System. Cells. 2022;11(5):764. Published 2022 Feb 22. doi:10.3390/cells11050764 Abstract The mammalian circadian system is a hierarchically organized system, which controls a 24-h periodicity in a wide variety of body and brain functions and physiological processes. There is increasing evidence that the circadian system modulates...
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24
May

For the First Time, Optogenetic Therapy Partially Restores Patient’s Vision

May 24, 2021
Source https://www.pittwire.pitt.edu/news/first-time-optogenetic-therapy-partially-restores-patient-s-vision Optogenetic therapy, or manipulating proteins and cells with light, is an advanced technology developed in the early 2000s that drove major discoveries about the inner workings of our brains. Yet, while actively researched in experimental animals, functional improvement using this method was never reported in humans—until now. In a paper published today in Nature...
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04
Apr

The Molecule Clock and Neurodegenerative Disease: A Stressful Time

April 4, 2021
Carter B, Justin HS, Gulick D and Gamsby JJ (2021) The Molecule Clock and Neurodegenerative Disease: A Stressful Time. Front. Mol. Biosci. 8:644747. doi: 10.3389/fmolb.2021.644747 Circadian rhythm dysfunction occurs in both common and rare neurodegenerative diseases. This dysfunction manifests as sleep cycle mistiming, alterations in body temperature rhythms, and an increase in symptomatology during the early evening...
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06
Mar

Mitochondrial solar sensitivity: evolutionary and biomedical implications

March 6, 2021
Sommer AP. Mitochondrial solar sensitivity: evolutionary and biomedical implications. Ann Transl Med. 2020 Mar;8(5):161. doi: 10.21037/atm.2019.11.100. PMID: 32310246; PMCID: PMC7154450. Depending on cellular demand or oxidative stress, mitochondria produce adenosine triphosphate (ATP) or reactive oxygen species (ROS), thereby controlling the entire scale of cellular energy supply or disease, respectively. While deficiency in ROS can compromise...
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09
Nov

Scoping Review of the Potential Health Effects of Exposure to Extremely Low-Frequency Electric and Magnetic Fields

November 9, 2019
Crit Rev Biomed Eng. 2019;47(4):323-347. doi: 10.1615/CritRevBiomedEng.2019030211 Abstract Previous studies suggest that extremely low-frequency (ELF) electric and magnetic fields (EMFs) may impact human health. However, epidemiologic studies have provided inconsistent results on the association between exposure to ELF EMFs and various health outcomes. This scoping review reports on primary investigations that were published during the ten-year...
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