Tag

Myocardial Ischemia
02
Jan

Intense light as anticoagulant therapy in humans

January 2, 2021
Oyama Y, Shuff S, Davizon-Castillo P, Clendenen N, Eckle T (2020) Intense light as anticoagulant therapy in humans. PLoS ONE 15(12): e0244792. https://doi.org/10.1371/journal.pone.0244792 Abstract Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole body Per2-/- mice found deficient platelet function and reduced...
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04
Dec

Circadian-Hypoxia Link and its Potential for Treatment of Cardiovascular Disease

December 4, 2020
Bartman CM, Eckle T. Circadian-Hypoxia Link and its Potential for Treatment of Cardiovascular Disease. Curr Pharm Des. 2019;25(10):1075-1090. doi:10.2174/1381612825666190516081612 Abstract Throughout evolutionary time, all organisms and species on Earth evolved with an adaptation to consistent oscillations of sunlight and darkness, now recognized as ‘circadian rhythm.’ Single-cellular to multi-system organisms use circadian biology to synchronize to the...
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