Tag

Light-dark cycle
08
Oct

Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation

October 8, 2021
Aiello I, Fedele MLM, Román F, Marpegan L, Caldart C, Chiesa JJ, Golombek DA, Finkielstein CV, Paladino N. Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation. Sci Adv. 2020 Oct 14;6(42):eaaz4530. doi: 10.1126/sciadv.aaz4530. PMID: 33055171; PMCID: PMC7556830. Abstract Circadian disruption negatively affects physiology, posing a global health threat that manifests in proliferative, metabolic,...
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13
May

Estrogens and the circadian system

May 13, 2021
Alvord VM, Kantra EJ, Pendergast JS. Estrogens and the circadian system. Semin Cell Dev Biol. 2021 May 8:S1084-9521(21)00083-5. doi: 10.1016/j.semcdb.2021.04.010. Epub ahead of print. PMID: 33975754. Abstract Circadian rhythms are ~24 h cycles of behavior and physiology that are generated by a network of molecular clocks located in nearly every tissue in the body. In...
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25
Apr

Disrupted Expression of Circadian Clock Genes in Patients with Bronchial Asthma

April 25, 2021
Chen HC, Chen YC, Wang TN, Fang WF, Chang YC, Chen YM, Chen IY, Lin MC, Yang MY. Disrupted Expression of Circadian Clock Genes in Patients with Bronchial Asthma. J Asthma Allergy. 2021 Apr 16;14:371-380. doi: 10.2147/JAA.S302508. PMID: 33888995; PMCID: PMC8057829. Abstract Purpose: Circadian clock is synchronized to the 24-hour day by the daily light-dark cycle...
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21
Apr

Shift-work causes negative impacts on health, affects men and women differently

April 21, 2021
APRIL 21, 2021 by University of Waterloo https://medicalxpress.com/news/2021-04-shift-work-negative-impacts-health-affects.html Shift-work and irregular work schedules can cause several health-related issues and affect our defense against infection, according to new research from the University of Waterloo. These health-related issues occur because the body’s natural clock, called the circadian clock, can be disrupted by inconsistent changes in the sleep-wake schedule...
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21
Apr

Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work

April 21, 2021
Stéphanie M. C. Abo et al. Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work, PLOS Computational Biology (2021). DOI: 10.1371/journal.pcbi.1008514 Abstract The circadian clock exerts significance influence on the immune system and disruption of circadian rhythms has been linked to inflammatory pathologies. Shift workers often experience circadian misalignment as their irregular work...
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