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Ischemia
Oyama Y, Shuff S, Davizon-Castillo P, Clendenen N, Eckle T (2020) Intense light as anticoagulant therapy in humans. PLoS ONE 15(12): e0244792. https://doi.org/10.1371/journal.pone.0244792 Abstract Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole body Per2-/- mice found deficient platelet function and reduced...
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Oyama Y, Bartman CM, Bonney S, Lee JS, Walker LA, Han J, Borchers CH, Buttrick PM, Aherne CM, Clendenen N, Colgan SP, Eckle T. Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Rep. 2019 Aug 6;28(6):1471-1484.e11. doi: 10.1016/j.celrep.2019.07.020. PMID: 31390562; PMCID: PMC6708043. https://pubmed.ncbi.nlm.nih.gov/31390562/
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