Tag

Insulin Resistance
13
Jun

Circadian clocks and insulin resistance

June 13, 2021
Stenvers, D.J., Scheer, F.A.J.L., Schrauwen, P. et al. Circadian clocks and insulin resistance. Nat Rev Endocrinol 15, 75–89 (2019). https://doi.org/10.1038/s41574-018-0122-1 Abstract Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a major cause of morbidity and mortality. The circadian timing system consists of a central brain clock in the hypothalamic suprachiasmatic nucleus and various peripheral...
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10
Dec

Chronic circadian shift leads to adipose tissue inflammation and fibrosis

December 10, 2020
Xiong X, Lin Y, Lee J, Paul A, Yechoor V, Figuero M, Ma K. Chronic circadian shift leads to adipose tissue inflammation and fibrosis. Mol Cell Endocrinol. 2020 Dec 4:111110. doi: 10.1016/j.mce.2020.111110. Epub ahead of print. PMID: 33285245. Abstract The circadian clock exerts temporal coordination of metabolic pathways. Clock disruption is intimately linked with the...
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