Tag

Circadian rhythms
13
May

Early life circadian rhythm disruption in mice alters brain and behavior in adulthood

May 13, 2022
Ameen RW, Warshawski A, Fu L, Antle MC. Early life circadian rhythm disruption in mice alters brain and behavior in adulthood. Sci Rep. 2022;12(1):7366. Published 2022 May 5. doi:10.1038/s41598-022-11335-0 Abstract Healthy sleep supports robust development of the brain and behavior. Modern society presents a host of challenges that can impair and disrupt critical circadian rhythms that...
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21
Oct

Photophysiological cycles in Arctic krill are entrained by weak midday twilight during the Polar Night

October 21, 2021
Cohen JH, Last KS, Charpentier CL, Cottier F, Daase M, Hobbs L, et al. (2021) Photophysiological cycles in Arctic krill are entrained by weak midday twilight during the Polar Night. PLoS Biol 19(10): e3001413. https://doi.org/10.1371/journal.pbio.3001413 Abstract Light plays a fundamental role in the ecology of organisms in nearly all habitats on Earth and is central...
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05
Oct

Desynchronized circadian clock and exposures to xenobiotics are associated with differentiated disease phenotypes

October 5, 2021
Makris, K. C. (2021). Desynchronized circadian clock and exposures to xenobiotics are associated with differentiated disease phenotypes. BioEssays, e2100159. https://doi.org/10.1002/bies.202100159 Abstract A paradigm shift in the human chronotoxicity of xenobiotics would study two-sided desynchronized phenomena of interfacial interactions between cyclic or periodic environmental insults and the endogenous response and recovery profile. These systems-based networks are under the influence of...
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02
Aug

Chronotype in individuals with schizophrenia: A meta-analysis

August 2, 2021
Linke M, Jankowski KS. Chronotype in individuals with schizophrenia: A meta-analysis. Schizophr Res. 2021 Jul 28;235:74-79. doi: 10.1016/j.schres.2021.07.020. Epub ahead of print. PMID: 34332427. Abstract Objective: Emerging evidence shows that evening chronotype is associated with mental health problems, especially mood disorders, but few studies have investigated its association with schizophrenia. Based on meta-analytic methods, we aimed...
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09
Jul

Chapter 21 – Retina and melanopsin neurons

July 9, 2021
La Morgia C, Carelli V, Sadun AA. Retina and melanopsin neurons. Handb Clin Neurol. 2021;179:315-329. doi: 10.1016/B978-0-12-819975-6.00020-0. PMID: 34225972. Abstract Melanopsin retinal ganglion cells (mRGCs) are the third class of retinal photoreceptors with unique anatomical, electrophysiological, and biological features. There are different mRGC subtypes with differential projections to the brain. These cells contribute to many...
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23
Jun

Night Matters—Why the Interdisciplinary Field of “Night Studies” Is Needed

June 23, 2021
Kyba, C.C.M.; Pritchard, S.B.; Ekirch, A.R.; Eldridge, A.; Jechow, A.; Preiser, C.; Kunz, D.; Henckel, D.; Hölker, F.; Barentine, J.; Berge, J.; Meier, J.; Gwiazdzinski, L.; Spitschan, M.; Milan, M.; Bach, S.; Schroer, S.; Straw, W. Night Matters—Why the Interdisciplinary Field of “Night Studies” Is Needed. J 2020, 3, 1-6. https://doi.org/10.3390/j3010001 Abstract The night has historically been neglected...
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16
May

Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet

May 16, 2021
Gutierrez Lopez DE, Lashinger LM, Weinstock GM, Bray MS. Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet. Cell Metab. 2021 May 4;33(5):873-887. doi: 10.1016/j.cmet.2021.03.015. Epub 2021 Mar 30. PMID: 33789092. Abstract The molecular circadian clock and symbiotic host-microbe relationships both evolved as mechanisms that enhance metabolic responses to environmental challenges....
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21
Apr

Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work

April 21, 2021
Stéphanie M. C. Abo et al. Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work, PLOS Computational Biology (2021). DOI: 10.1371/journal.pcbi.1008514 Abstract The circadian clock exerts significance influence on the immune system and disruption of circadian rhythms has been linked to inflammatory pathologies. Shift workers often experience circadian misalignment as their irregular work...
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19
Mar

Impact of Circadian Disruption on Cardiovascular Function and Disease

March 19, 2021
Chellappa SL, Vujovic N, Williams JS, Scheer FAJL. Impact of Circadian Disruption on Cardiovascular Function and Disease. Trends Endocrinol Metab. 2019 Oct;30(10):767-779. doi: 10.1016/j.tem.2019.07.008. Epub 2019 Aug 16. PMID: 31427142; PMCID: PMC6779516. Abstract The circadian system, that is ubiquitous across species, generates ∼24 h rhythms in virtually all biological processes, and allows them to anticipate...
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17
Mar

Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection

March 17, 2021
Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection Miguel Meira eCruz, Masaaki Miyazawa, David Gozal European Respiratory Journal Jan 2020, 2001023;  DOI: 10.1183/13993003.01023-2020 Circadian deregulation and poor or insufficient sleep may facilitate COVID19 infection and severity SARS coronavirus 2 (SARS-CoV-2), the etiologic agent of the pandemic coronavirus disease 2019 (COVID-19), is a newly found member of the Coronaviridae...
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