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Circadian Rhythm Disruption
Jennifer A. Liu, O. Hecmarie Meléndez-Fernández, Jacob R. Bumgarner, Randy J. Nelson,Effects of light pollution on photoperiod-driven seasonality, Hormones and Behavior,Volume 141, 2022, 105150, ISSN 0018-506X,https://doi.org/10.1016/j.yhbeh.2022.105150. Highlights • Circadian disruption disrupts photoperiodic time measurement and seasonal adaptations. •Light at night disrupts reproduction, immune function and metabolism, a crucial proxy for fitness. https://doi.org/10.1016/j.yhbeh.2022.105150
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New mechanism highlights risks of circadian disruption and supports timed cancer treatment. Source: https://www.eurekalert.org/news-releases/497871# NEWS RELEASE 30-APR-2019 Disrupting normal circadian rhythms promotes tumor growth and suppresses the effects of a tumor-fighting drug, according to a new study publishing April 30 in the open-access journal PLOS Biology by Yool Lee, Amita Sehgal, and colleagues at the University of Pennsylvania....
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Leso, V.; Fontana, L.; Caturano, A.; Vetrani, I.; Fedele, M.; Iavicoli, I. Impact of Shift Work and Long Working Hours on Worker Cognitive Functions: Current Evidence and Future Research Needs. Int. J. Environ. Res. Public Health 2021, 18, 6540. https://doi.org/10.3390/ijerph18126540 Abstract Particular working conditions and/or organization of working time may cause important sleep disturbances that have been proposed...
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Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends in Pharmacological Sciences. 2018 Sep;39(9):812-827. DOI: 10.1016/j.tips.2018.07.003. Highlights Although circadian rhythm disruption (CRD) was typically considered to be a risk for chronic diseases solely for shift workers (∼20%...
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Zhang, Z., Zeng, P., Gao, W. et al. Circadian clock: a regulator of the immunity in cancer. Cell Commun Signal 19, 37 (2021). https://doi.org/10.1186/s12964-021-00721-2 Abstract The circadian clock is an endogenous timekeeper system that controls and optimizes biological processes, which are consistent with a master circadian clock and peripheral clocks and are controlled by various genes. Notably, the disruption of...
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de Assis, L.V.M., Oster, H. The circadian clock and metabolic homeostasis: entangled networks. Cell. Mol. Life Sci. (2021). https://doi.org/10.1007/s00018-021-03800-2 Abstract The circadian clock exerts an important role in systemic homeostasis as it acts a keeper of time for the organism. The synchrony between the daily challenges imposed by the environment needs to be aligned with biological processes...
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Fatima Y, Bucks RS, Mamun AA, Skinner I, Rosenzweig I, Leschziner G, Skinner TC. Shift work is associated with increased risk of COVID-19: Findings from the UK Biobank cohort. J Sleep Res. 2021 Mar 8:e13326. doi: 10.1111/jsr.13326. Epub ahead of print. PMID: 33686714. Abstract Despite the strong evidence on circadian rhythm disruption in shift workers...
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