Tag

Circadian Dysfunction
Ikegami, K., Refetoff, S., Van Cauter, E. et al. Interconnection between circadian clocks and thyroid function. Nat Rev Endocrinol 15, 590–600 (2019). https://doi.org/10.1038/s41574-019-0237-z Abstract Circadian rhythmicity is an approximately 24-h cell-autonomous period driven by transcription–translation feedback loops of specific genes, which are referred to as ‘circadian clock genes’. In mammals, the central circadian pacemaker, which is located in the hypothalamic...
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Nankivell, V.A., Tan, J.T.M., Wilsdon, L.A. et al. Circadian disruption by short light exposure and a high energy diet impairs glucose tolerance and increases cardiac fibrosis in Psammomys obesus. Sci Rep 11, 9673 (2021). https://doi.org/10.1038/s41598-021-89191-7 Abstract Type 2 diabetes mellitus (T2DM) increases cardiac inflammation which promotes the development of cardiac fibrosis. We sought to determine the impact of circadian disruption on...
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