Tag

Allostasis
22
Dec

The hypothalamic-pituitary-adrenal axis as a substrate for stress resilience: Interactions with the circadian clock.

December 22, 2019
Front Neuroendocrinol. 2019 Dec 18:100819. doi: 10.1016/j.yfrne.2019.100819. [Epub ahead of print] Abstract Stress, primarily processed via the hypothalamic-pituitary-adrenal (HPA) axis, engages biological pathways throughout the brain and body which promote adaptation and survival to changing environmental demands. Adaptation to environmental challenges is compromised when these pathways are no longer functioning optimally. The physiological and behavioral mechanisms...
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17
Nov

The physiological significance of the circadian dynamics of the HPA axis: Interplay between circadian rhythms, allostasis and stress resilience.

November 17, 2019
Horm Behav. 2019 Apr;110:77-89. doi: 10.1016/j.yhbeh.2019.02.018. Epub 2019 Mar 15. Abstract Circadian time-keeping mechanisms preserve homeostasis by synchronizing internal physiology with predictable variations in the environment and temporally organize the activation of physiological signaling mechanisms to promote survival and optimize the allocation of energetic resources. In this paper, we highlight the importance of the robust circadian...
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