Day

May 24, 2021
24
May

Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction

May 24, 2021
Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction Abstract Hypogonadism is an endocrine disorder characterized by inadequate serum testosterone production by the Leydig cells of the testis. It is triggered by alterations in the hypothalamic–pituitary–gonadal axis. Erectile dysfunction (ED) is another common disorder in men that involves an alteration...
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24
May

Partial recovery of visual function in a blind patient after optogenetic therapy

May 24, 2021
Sahel, JA., Boulanger-Scemama, E., Pagot, C. et al. Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med (2021). https://doi.org/10.1038/s41591-021-01351-4 Abstract Optogenetics may enable mutation-independent, circuit-specific restoration of neuronal function in neurological diseases. Retinitis pigmentosa is a neurodegenerative eye disease where loss of photoreceptors can lead to complete blindness. In a blind patient, we combined...
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24
May

For the First Time, Optogenetic Therapy Partially Restores Patient’s Vision

May 24, 2021
Source https://www.pittwire.pitt.edu/news/first-time-optogenetic-therapy-partially-restores-patient-s-vision Optogenetic therapy, or manipulating proteins and cells with light, is an advanced technology developed in the early 2000s that drove major discoveries about the inner workings of our brains. Yet, while actively researched in experimental animals, functional improvement using this method was never reported in humans—until now. In a paper published today in Nature...
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24
May

John Bucher, who studied toxic agents from A to Z, retires from NIEHS

May 24, 2021
#NTPtox senior scientist John Bucher, Ph.D., retired in April after nearly four decades at the institute. His scientific achievements, innovative thinking, and mentorship will leave a lasting influence, according to colleagues. https://t.co/8PjTc7Q70P pic.twitter.com/BZyquwrhbi— NIEHS (@NIEHS) May 24, 2021 NIEHS News Environmental Factor May 2021 During almost four decades at the institute, he brought innovation to...
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24
May

How bacteria use electric fields to reach surfaces

May 24, 2021
Chong P, Erable B, Bergel A. How bacteria use electric fields to reach surfaces. Biofilm. 2021 Apr 8;3:100048. doi: 10.1016/j.bioflm.2021.100048. PMID: 33997766; PMCID: PMC8090995. Abstract Electrotaxis is the property of cells to sense electric fields and use them to orient their displacement. This property has been widely investigated with eukaryotic cells but it remains unclear...
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